BPC-157 (“Body Protection Compound 157”) is a synthetic 15-amino-acid peptide based on a sequence from a protein found in human gastric juice. It supplies 10 mg of a standard 70 mg GLOW vial, and it is one of the most discussed and least clinically tested research peptides.
Compound snapshot
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Length | 15 amino acids (pentadecapeptide) |
| Molecular formula | C₆₂H₉₈N₁₆O₂₂ |
| Molecular weight | ≈1419.5 g/mol |
| CAS number | 137525-51-0 |
| Common forms | Free base or acetate salt; an arginate salt is also sold |
| Regulatory status | Not approved by any drug regulator; on the WADA prohibited list (S0) since 2022 |
What the research covers
Most published BPC-157 work comes from a small number of research groups, mainly in Croatia, and uses rodent models. These studies report faster healing across a wide range of injury models, including tendon, ligament, muscle, skin and gastrointestinal lesions. Proposed mechanisms include effects on blood-vessel growth (angiogenesis), the nitric-oxide system, and growth-factor signaling.
A 2021 review in Frontiers in Pharmacology summarizes the wound-healing literature. A 2025 systematic review in orthopaedic sports medicine found that the evidence base is overwhelmingly preclinical. Human data is limited to a handful of small reports, and a Phase I trial did not publish results.
What is still unknown
- Human efficacy: no adequately powered controlled human trials have been published.
- Long-term safety: there is little human safety data. Because it promotes angiogenesis, researchers have raised theoretical concerns that remain unresolved.
- Replication: much of the literature comes from a single research network, and independent replication is limited.
Role in the GLOW blend
In GLOW, BPC-157 sits alongside GHK-Cu and TB-500. The rationale is that each compound shows up in tissue-repair models through a different pathway. The combination itself hasn’t been studied in published research. Read what the research says about GLOW’s components for a side-by-side view.
Handling notes for lab work
- Salt form matters for exact mass. Check whether a COA reports free base, acetate or arginate.
- Lyophilized BPC-157 is typically stored at −20 °C and kept dry. See the reconstitution and storage guide.
- The expected [M+H]⁺ is about 1420 Da. A mass spec result far from that means the product isn’t what the label says.
Key references
- Seiwerth S, et al. Stable gastric pentadecapeptide BPC 157 and wound healing. Front Pharmacol. 2021. Full text
- Vasireddi N, et al. Emerging use of BPC-157 in orthopaedic sports medicine: a systematic review. HSS J. 2025. PubMed
- PubChem compound record: BPC-157 (CID 9941957). PubChem
This page is educational and summarizes published research. It is not medical advice. BPC-157 is not approved for human use and is prohibited in sport. Research-grade material is for laboratory use only.